This study aimed to evaluate the impact of SENS oversizing on ISR of SFA. COF could produce continuous mechanical stimulation of the arterial wall, which can increase neointimal hyperplasia and lead to significant ISR. The chronic outward force (COF) exerted by a SENS is another important factor to cause restenosis, and several investigations evaluated the effect of SENS oversizing on the risk of in-stent restenosis (ISR). The mechanical stresses to the SFA are associated with an increased risk of stent fracture and subsequent significant restenosis. SFA stents are under dynamic stress to external forces including bending, twisting, torsion, elongation, foreshortening and external compression. Implanted SENS is commonly oversized in the SFA, especially at the distal portion due to tapered diameter of SFA for long SENS. However, stent size influences clinical outcomes. The self-expanding nitinol stent (SENS) for superficial femoral artery (SFA) lesions is morphologically and clinically superior to balloon angioplasty. Therefore, COF was an important factor of restenosis following distal SFA stenting.īalloon angioplasty and stent implantation are popular in patients with peripheral artery disease (PAD). Optimal sizing of the SFA stent is important to reduce the incidence of restenosis. ConclusionsĬOF is an important cause of restenosis in the distal portion of the SFA stent. The neointimal area was 5.37 ± 1.15 mm 2 vs. The vessel diameter was 4.04 ± 0.40 mm (control group) vs 4.45 ± 0.63 mm (oversized group), and the implanted stent diameter was 5.27 ± 0.46 mm vs. All 11 pigs survived for 4 weeks after SENS implantation. ISR incidence was higher at the distal stent (37.3% vs 52.6%, P = 0.029). In the long SFA stent, stent-to-vessel ratio was significantly higher in the distal stent than in the proximal stent (1.3 ± 0.2 vs. The ratio of the diameter of the stent to the reference vessel was 1.3 ± 0.24 at the proximal portion and 1.53 ± 0.27 at the distal portion ( P < 0.001). The baseline diameter was 6.8 ± 0.71 mm and length were 97.0 ± 33.8 mm for the SENS. We analyzed 65 SENS in 61 patients with follow-up angiography at 6 months to 1 year. Excised stented arteries were evaluated by histopathologic analysis. In addition, porcine model with implanted SENS was used to evaluate the impact of COF on angiographic and histopathologic outcomes at 1 month. In patients with implanted SENS in SFA, intimal hyperplasia especially between proximal segment and distal segment was evaluated by quantitative angiography, and the impact of COF on mid-term angiographic outcomes was investigated. This study aimed to investigate the impact of COF of oversizing SENS on ISR of SFA. Vascular diseases typically result from the hardening and narrowing of blood vessels and high blood pressure.Self-expanding nitinol stent (SENS) implantation is commonly oversized in the superficial femoral artery (SFA), and leads to chronic outward force (COF) and in-stent restenosis (ISR). We perform the highest volume of catheterization procedures in the county and our patient outcomes place us in the top 2 percent of cardiac cath labs in the country.

As a STEMI-receiving hospital, our paramedics can consult with us while transporting a patient directly to the cath lab.Our most recent average time of under 60 minutes beats the national benchmark of 90 minutes. We have consistently low 'door-to-balloon' times, or the time it takes for a lifesaving procedure during a severe heart attack.

Ephemeral artery